Gene: [03^/PDHB] pyruvate dehydrogenase, E1 beta polypeptide;

FUN

[1] Systematic name: pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating).
[2] The reaction catalyzed: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO(2)."

FAG

Genes for alpha subunit of pyruvate dehydrogenase have been mapped to chromosomes X and 4 (GEM:0Xp221/PDHA1 and GEM:04q2/PDHA2)."

REF

CLO,COD,EXP "Ho L &: BBRC, 150, 904-908, 1988
CLO,COD,SEQ,FAG "Koike K &: PNAS, 85, N1, 41-45, 1988
LOC,FAG "Olson S &: AJHG, 46, N2, 340-349, 1990

SWI

 SWISSPROT: P11177

KEY

mito, lip, carb

CLA

coding, basic

LOC

03 p13-q23

MIM

 MIM: 179060

EZN

 ENZYME: 1.2.4.1